Nitric oxide reductase (cytochrome c) () is an enzyme with systematic name nitrous oxide:ferricytochrome-c oxidoreductase. This enzyme catalyses the following chemical reaction
2 nitric oxide + 2 ferrocytochrome c + 2 H+ nitrous oxide + 2 ferricytochrome c + H2O
The enzyme from Pseudomonas aeruginosa contains a dinuclear centre.
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