Highland Avenue may refer to:

Historic districts Highland Avenue Historic District (Birmingham, Alabama), listed on the National Register of Historic Places in Birmingham, Alabama Highland Avenue Historic District (Lexington, Missouri), listed on the National Register of Historic Places in Lafayette County, Missouri

Streets Highland Avenue (Atlanta), also North Highland Avenue Highland Avenue (Augusta, Georgia) Highland Avenue (Baltimore) Highland Avenue (Los Angeles)

Transportation Highland Avenue station (NJ Transit) Highland Avenue station (SEPTA)