Jatun Mayu (Quechua hatun, jatun big, great, mayu river,katari.org Aymara-Spanish Dictionary: Jatun (adj.) - Grande, superior, principal. Mayu (s.) - Río. "great river") is a Bolivian river in the Cochabamba Department, Esteban Arce Province, in the Anzaldo and Sacabamba Municipalities. Its waters flow to Laguna Angostura.

Upstream the river is called Challaque. Its direction is mainly north west as it flows along Challaque, Sacabamba, Matarani and Apillapa. Before reaching the town Cliza the name of the river changes to the Siches RiverAnzaldo Municipality: population data and map or Cliza River.lib.utexas.edu Detailed map of the area It is the main tributary of Laguna Angostura.

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