Non-specific polyamine oxidase (, polyamine oxidase, Fms1, AtPAO3) is an enzyme with systematic name polyamine:oxygen oxidoreductase (3-aminopropanal or 3-acetamidopropanal-forming). This enzyme catalyses the following chemical reaction
(1) spermine + O2 + H2O spermidine + 3-aminopropanal + H2O2 (2) spermidine + O2 + H2O putrescine + 3-aminopropanal + H2O2 (3) N1-acetylspermine + O2 + H2O spermidine + 3-acetamidopropanal + H2O2 (4) N1-acetylspermidine + O2 + H2O putrescine + 3-acetamidopropanal + H2O2
This enzyme is flavoprotein (FAD).
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