Valine dehydrogenase (NAD+) () is an enzyme with systematic name L-valine:NAD+ oxidoreductase (deaminating). This enzyme catalyses the following chemical reaction

The enzyme from Streptomyces spp. uses nicotinamide adenine dinucleotide as its cofactor but has no activity with NADP+.

See also Valine dehydrogenase (NADP+)

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