Masterson is a surname that originated in the British Isles. It is most commonly found in Ireland where it has often been used as the anglicised form of a Fermanagh sept Mac an Mhaighistir (McMaster), not to be confused with the Scottish McMaster(s). Notable people with the surname include:

Alanna Masterson (born 1988), American actress Bat Masterson (1853–1921), gunfighter, lawman, sports writer Chase Masterson (born 1963), American actress Christina Masterson (born 1989), American actress Christopher Masterson (born 1980), American actor Danny Masterson (born 1976), American actor, older brother of Christopher Masterson Emma Masterson (born 1977), Thai actress, model and television presenter Fay Masterson (born 1974), English actress James F. Masterson (1926–2010), American psychiatrist Jordan Masterson (born 1986), American actor Justin Masterson (born 1985), American baseball player Kelly Masterson, American screenwriter Lisa Masterson (born 1966) OB/GYN on the talk show The Doctors Luke Masterson (born 1998), American football player Martha Gay Masterson (1837–1916), American settler and diarist Mary Stuart Masterson (born 1966), American actress Paul Masterson, Northern Irish music producer Paul Masterson (baseball) (1915–1997), American Major League Baseball pitcher Reba Byrd Masterson, Texas geologist Rod Masterson (1945–2013), American actor Ronnie Masterson (1926–2014), Irish actress Valerie Masterson (born 1937), English opera singer Walt Masterson (1920–2008), American baseball pitcher Walter Masterson (born 1978), American comedian Wayne Masterson (1959–1991), British scientist William Masterson (1910–1984), American priest and educator

Fictional characters

Teresa Masterson, a character from the Australian soap opera Home and Away; portrayed by Simone McAullay Jill Masterson, from Goldfinger Cookie Masterson, character from American trivia party game You Don't Know Jack; portrayed by Tom Gottlieb Jen Masterson, fictional character on Canadian cartoon series 6teen Henry Masterson, fictional character on the American cartoon series Transformers Animated