Alcohol-forming fatty acyl-CoA reductase (, FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase. This enzyme catalyses the following chemical reaction
a long-chain acyl-CoA + 2 NADPH + 2 H+ a long-chain alcohol + 2 NADP+ + coenzyme A
The enzyme has been characterized from the plant Simmondsia chinensis. There are two known human isozymes, encoded by the genes FAR1 and FAR2.
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