Scaccia is an Italian surname. Notable people with the surname include:
Angelo Scaccia, American politician Angelo Maria Scaccia ( 1690–1761), Italian composer and violinist Beatrice Scaccia (born 1978), Italian visual artist Fabrizio Scaccia (born 1984), American football player Mario Scaccia (1919–2011), Italian actor and writer Mike Scaccia (1965–2012), American musician Mónica Lei Scaccia, Venezuelan beauty pageant contestant Pino Scaccia (1946–2020), pseudonym for Italian journalist Giuseppe Scaccianoce (1564–1634), Italian legal scholar