Guitton or Guiton is a French surname. Notable persons with that surname include:
Persons with the surname Guitton Abraham Duquesne-Guitton (1648–1724), French naval commander Helga Guitton (born 1942), German radio and TV presenter Jean Guitton (1901–1999), French Catholic philosopher
Persons with the surname Guiton Jean Guiton (1585–1654), Mayor of La Rochelle and naval commander