Rendon or Rendón is a surname. Notable people with the surname include:
Ana Rendón (born 1986), Colombian archer Andrés Rendón, Colombian karateka Anthony Rendon (born 1990), American baseball player Anthony Rendon (politician), American politician Daniel Rendón Herrera, Colombian drug trafficker Del Rendon (1965–2005), American musician Diego Luis Rendón Urrea (born 1967), Colombian Roman Catholic bishop Estanislao Rendón (1806-1874), Venezuelan politician James Rendón (born 1985), Colombian racewalker John Toro Rendón (born 1958), Colombian football referee Juan José Rendón (born 1964), Venezuelan publicist Manuel Rendón Seminario (1894–1982), Ecuadorian painter María Chacón Rendón, Bolivian lawyer and politician Marianne Rendón, American actress Valentina Rendón (born 1975), Colombian actress and singer