Hilsum is a surname. Notable people with the surname include:
Cyril Hilsum (1925–2026), British physicist and academic François Hilsum (1929–2020), French political activist and journalist Ian Hilsum (born 1981), English cricketer Karen Burt (née Hilsum; 1954–1997), British engineer and campaigner Lindsey Hilsum (born 1958), English television journalist and writer