Belisle or Bélisle is a surname, derived from an island off the coast of France called “Belle Ile” (Beautiful Isle). Notable people with the name include:

Danny Belisle (1937–2022), Canadian ice hockey player and coach Eugene Belisle (1910–1983), American Olympic rower Ève Bélisle (born 1979), Canadian curler and amateur ornithologist Jerome J. Belisle (1932–2022), American businessman and politician Khalid Belisle (born 1981), Belizean politician and mayor of Belmopan Kirk Belisle (died 2003), Belizean stabbing victim Lyndsay Belisle (born 1977), Canadian freestyle wrestler Matt Belisle (born 1980), American baseball pitcher Mitch Belisle (born 1985), American lacrosse player Polin Belisle (born 1966), Olympic marathon runner for Belize and Honduras Rhéal Bélisle (1919–1992), Canadian politician from Ontario Richard Bélisle (born 1946), Canadian politician from Quebec Roger Belisle (born 1947), Canadian ice hockey player