This is a list of films which have placed number one at the weekend box office in Italy during 2010.
Number-one films †This implies the highest-grossing movie of the year. # Date Film Weekend GrossTotal Gross 1 Sherlock Holmes $6,582,433 $26,955,437 2 Me, Them and Lara $6,753,283 $21,347,896 3 Avatar † $13,889,941 $83,498,193 4 $12,383,549 5 $10,357,947 6 $7,783,01 7 $5,181,248 8 $3,767,803 9 Parents and Children: Shake Well Before Using $3,802,776 $11,455,266 10 Alice in Wonderland $11,115,961 $39,952,697 11 $8,311,436 12 $4,307,666 13 How to Train Your Dragon $1,630,412 $9,979,666 14 La vita è una cosa meravigliosa $2,287,044 $6,161,728 15 The Ghost Writer $1,382,472 $4,811,454 16 Clash of the Titans $4,286,144 $10,275,464 17 $2,133,330 18 Iron Man 2 $4,701,280 $9,979,666 19 $2,073,896 20 Robin Hood $5,172,957 $14,676,791 21 Prince of Persia: The Sands of Time $1,909,536 $8,912,558 22 Sex and the City 2 $2,072,658 $7,802,889 23 $896,600 24 The Hole $495,714 $2,094,728 25 The A-Team $1,111,167 $3,143,928 26 $396,533 27 The Twilight Saga: Eclipse $4,793,904 $20,711,944 28 Toy Story 3 $3,021,009 $18,855,881 29 $2,011,511 30 $1,245,241 31 $838,708 32 $500,852 33 Marmaduke $940,960 $2,503,450 34 The Sorcerer's Apprentice $16,968,032 $9,571,490 35 Shrek Forever After $4,504,291 $23,451,561 36 $3,637,448 37 $1,915,433 38 Vampires Suck $2,483,735 $6,000,711 39 Inception $3,556,167 $15,459,083 40 Benvenuti al Sud $5,231,564 $43,015,634 41 $6,242,77 42 $5,528,640 43 $3,889,528 44 Men vs. Women $4,222,767 $18,452,860 45 $3,582,226 46 $1,869,690 47 Harry Potter and the Deathly Hallows – Part 1 $10,193,771 $23,988,197 48 $4,625,564 49 Tangled $2,710,588 $14,670,362 50 $1,918,925 51 Natale in Sudafrica $4,282,724$24,898,572 52 $8,073,079 53 The Santa Claus Gang $5,763,680 $29,125,119
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