Houlihan or O'Houlihan (; feminine ) is a surname of Irish Gaelic origin, from the Irish meaning "proud". Notable people with the surname include:

Adam Houlihan (born 1978), former Australian rules footballer Christopher Houlihan (born 1987), American concert organist Con Houlihan (1925–2012), Irish sportswriter Damian Houlihan (born 1975), former Australian rules footballer Gerard Houlihan, Irish retired Gaelic footballer Jim Houlihan (1898–1967), Irish sportsperson Joan Houlihan, American poet John C. Houlihan (1910–1986), American politician, the 43rd mayor of Oakland, California John J. Houlihan (1923–2003), American politician, Illinois state representative Mike Houlihan (born 1969), retired Irish sportsperson Pat Houlihan (1929–2006), English snooker player Patrick Houlihan (1889–1963), Irish politician Ryan Houlihan (born 1982), Australian rules footballer Shelby Houlihan (born 1993), American middle-distance runner Tim Houlihan (born 1989), Australian rules footballer Timmy Houlihan (born 1982), Irish sportsperson

See also Houlihan's, an American restaurant and bar chain Houlihan Lokey, independent, advisory-focused, global investment bank Houlihan Stadium or Tampa Stadium, a sports venue in Tampa, Florida Houlihan Smith & Company, investment banking firm Jim Houlihan Park at Jack Coffey Field, a baseball venue on the Rose Hill campus of Fordham University in Bronx, New York Cathleen ni Houlihan, a one-act play by Irish playwright William Butler Yeats Kathleen Ni Houlihan, a mythical symbol and emblem of Irish nationalism found in literature and art Margaret "Hot Lips" Houlihan, a fictional character in the M*A*S*H franchise In cattle roping the houlihan is a one-swing flip shot at a calf traveling in front of you from left to right Holohan, an alternative spelling Hooligan Houlahan Wes Hoolahan O'Houlihan (dynasty)