James Mays may refer to:
James C. Mays (1953–2022), Canadian historian James Dixon Mays (born 1986), American-born naturalized Central African basketball player James Henry Mays (1868–1926), U.S. Representative James Luther Mays (1921–2015), Old Testament scholar James P. Mays (fl. 1860s–1870s), member of the South Carolina House of Representatives
See also Jayma Mays (born 1979), American actress Jimmy Mays (fl. 1970s–2010s), American polymer scientist, academic, and author James May (disambiguation)