During the 1999–2000 Dutch football season, PSV Eindhoven competed in the Eredivisie.

Season summary PSV claimed the Eredivisie title with a margin of 16 points between them and second-placed Heerenveen, scoring 105 goals in the process.

Kit PSV's kit was manufactured by Nike and sponsored by Philips

First-team squad Squad at end of season

Transfers

In Johann Vogel - Grasshoppers Mark van Bommel - Fortuna Sittard Ivica Kralj - Porto Eric Addo - Club Brugge, fl.5.9m

Out Gilles De Bilde - Sheffield Wednesday, August

Results

Champions League

Third qualifying round FC Zimbru Chișinău 0-0 PSV PSV 2-0 FC Zimbru Chișinău

Group stage

References