Lukšić is a Croatian surname. It may refer to:
Andrónico Luksic (1926–2005) Chilean businessman of Croatian origin and founder of the Luksic Group Carl J. Luksic (1921–2009), American flying ace during World War II Guillermo Luksic Craig (1956–2013), Chilean businessman, son and heir of Andrónico Luksic Igor Lukšić (1976), Montenegrin politician, Prime Minister of Montenegro 2010–2012 Igor Lukšič (born 1961), Slovenian political scientist and politician Kaštel Lukšić, a town within the administrative area of Kaštela in Dalmatia, Croatia Oliver Luksic (born 1979), German politician
Another version of the same surname is Lussich: Antonio Lussich (1848–1928), Uruguayan sailor, arboriculturist and writer Lussich Arboretum, an artificial forest in Uruguay Lussich Cove, a cove at the south Shetland Islands