John Fuller Atkins is a research professor at University College Cork and a member of the Royal Irish Academy since 2003. Atkins was the first Irish national to be elected as a member of the EMBO Organization. In 2002 Science Foundation Ireland appointed Atkins as its first Director of Biotechnology. Atkins is also an honorary Professor of Genetics at his alma mater Trinity College, Dublin.
Research Shortly after Crick and Brenner established the triplet nature of genetic decoding John Atkins showed that mRNA molecules are not always translated in a triplet manner.Riyasaty S, Atkins JF. External suppression of a frameshift mutant in salmonella. J Mol Biol. 1968 Jun 28;34(3):541–57. Since then Atkins focused on aspects of the genetic decoding that are in defiance of the standard genetic code – phenomena collectively described as Recoding.Atkins, John F.; Gesteland, Raymond F.Recoding: Expansion of Decoding Rules Enriches Gene Expression. Springer. Recoding challenges the generality of the genetic decoding and encompasses phenomena such as programmed ribosomal frameshifting that violates triplet character of the genetic readout. Proteinogenic amino acids that are not part of the genetic code, e.g. the 21st amino acid selenocysteine and the 22nd amino acid pyrrolysine are also subjects of Recoding.John F. Atkins and Ray Gesteland (2002). "The 22nd Amino Acid". Science 296 (5572): 1409–1410. doi:10.1126/science.1073339. John Atkins is an active proponent of the RNA World hypothesis and is an editor of The RNA World and RNA Worlds books.Gesteland, Raymond F.; Cech, Thomas; Atkins, John F. (2006). The RNA world: the nature of modern RNA suggests a prebiotic RNA world. Plainview, N.Y: Cold Spring Harbor Laboratory Press. .Atkins, John F.; Gesteland, Raymond F.; Cech, Thomas. (2011). RNA Worlds: From Life’s Origins to Diversity in Gene Regulation. Plainview, N.Y: Cold Spring Harbor Laboratory Press. . His research activities include a search for modern protein-free RNA-based life forms.Ledford H. Life-changing experiments: The biological Higgs. Nature 483, 528–530 (29 March 2012) doi:10.1038/483528a In 2013 John Atkins organized installation of Charles Jencks sculpture ?What is Life? in Irish National Botanic Gardens. In 2021 a family of RNA bacteriophages Atkinsviridae was named in recognition of his involvement in the discovery of Bacteriophage MS2 lysin protein.Julie Callanan, Stephen R. Stockdale, Evelien M. Adriaenssens, Jens H. Kuhn, Janis Rumnieks, Mark J. Pallen, Andrey N. Shkoporov, Lorraine A. Draper, R. Paul Ross, Colin Hill (2021). "Leviviricetes: expanding and restructuring the taxonomy of bacteria-infecting single-stranded RNA viruses." MICROBIAL GENOMICS doi:10.1099/mgen.0.000686
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External links RNA Worlds Book ?What is Life? sculpture