Nesse may refer to:
Nesse (Hörsel), a river in Thuringia, Germany, tributary to the Hörsel, 54.5 km long Nesse (Werra), a river in North Hessen, Germany, tributary to the Werra, 5.9 km long Nesse, Dornum, a village in Dornum municipality, Aurich District, in Lower Saxony, Germany Nesse, Loxstedt, a village in Loxstedt municipality, Cuxhaven District, in Lower Saxony, Germany Nesse Valley Railway, the rail line of the Gotha–Leinefelde railway between Gotha and Behringen in Thuringia, Germany
People Nesse Godin (born 1928), Lithuanian American Holocaust survivor, who dedicated her adult life to teaching and sharing memories of the Holocaust Johannes Nesse (1891–1948), Norwegian newspaper editor Åse-Marie Nesse (1934–2001), Norwegian philologist, translator and poet Randolph M. Nesse (1948–), American physician and evolutionary biologist
See also Mittleres Nessetal, a collective municipality in Gotha District, Thuringia, Germany Nesse-Apfelstädt, a municipality in Gotha District, Thuringia, Germany Nesseaue, a collective municipality in Gotha District, Thuringia, Germany