Thomas Willoughby (1593–?) was a North American colonist.

Thomas Willoughby may also refer to:

Thomas Willoughby (MP for Downton) (died before 1596), MP for Downton (UK Parliament constituency) Thomas Willoughby (MP for Lincolnshire) (died 1418), MP for Lincolnshire (UK Parliament constituency) Thomas Willoughby (MP) (1694–1742), English politician Thomas Willoughby, 1st Baron Middleton (1672–1729), English politician Thomas Willoughby, 4th Baron Middleton (1728–1781), English nobleman Thomas Willoughby, 11th Baron Willoughby of Parham (1602–1691/92), English peer Thomas Willoughby (Virginia), settler in 1610 Tom Willoughby (1889–1964), Australian rules footballer

See also