Thomas Preston (died 1604) was an English politician.
He was the only son of John Preston of Preston Patrick, Westmorland.
He was a Justice of the Peace for Lancashire and Westmorland and appointed High Sheriff of Lancashire for 1584–85.
He was a member (MP) of the parliament of England for Knaresborough in 1589.
He married Anne or Margaret, the daughter of John Westby of Mowbrick, Lancashire; they had one son, John.
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