Sophia of Wittelsbach (1170–1238) was a daughter of Otto I Wittelsbach (Count Palatine and later Duke of Bavaria) and his wife Agnes of Loon.
In 1196, Sophia married Landgrave Hermann I of Thuringia; she was his second wife. They had the following children: Irmgard (b. 1197), married in 1211 to Count Henry I of Anhalt Louis IV (1200–1227) Herman (1202–1216) Conrad (1204–1247), grand master of the Teutonic Knights Henry Raspe (1204–1247) Agnes, married twice: in 1225 to Henry "the Profane" of Babenberg (1208–1228), a son of Margrave Leopold VI of Austria in 1229 to Duke Albert I of Saxony ( – 1261)
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