478th may refer to:

478th Aeronautical Systems Wing (478 ASW), wing of the United States Air Force based out of Wright-Patterson Air Force Base, Ohio 478th Bombardment Squadron, inactive United States Air Force unit 478th Tactical Fighter Squadron, inactive United States Air Force unit

See also 478 (number) 478, the year 478 (CDLXXVIII) of the Julian calendar 478 BC