William Charlton may refer to:
Politicians William Andrew Charlton (1841–1930), Canadian politician William Charlton (died 1567), MP for Shropshire William Charlton (Wisconsin politician) (1831–1908), American farmer and politician
Sportsmen Billy Charlton (1900–1981), English footballer Bill Charlton (1912–1998), English footballer
Others William Browell Charlton (1855–1932), British trade union leader William Charlton, musician in The Strange Death of Liberal England Bill Charlton (businessman), on This Is the Law