Jessie Smith may refer to:
Jessie Payne Margoliouth (1856–1933), née Smith, Syriac scholar Jessie Willcox Smith (1863–1935), American illustrator Jessie Evans Smith (born Jessie Ella Evans; 1902–1971), wife of Joseph Fielding Smith Jessie Maye Smith (1907–2005), American ornithologist J. L. Smith (born Jessie L. Smith), American baseball pitcher Jessie Carney Smith (born 1930), American librarian and educator Jessie Smith (singer) (1941–2021), American R&B vocalist
See also Jessica Smith (disambiguation) Jesse Smith (disambiguation)