Mohammad Hosseini, or other spelling variations, may refer to:
Mohammed Tahir al-Husayni (1842–1908), Palestinian Hanafi cleric Mohammad Hosseini (politician) (born 1961), Iranian politician Mohamad Ali El Husseini (born 1974), Saudi Arabian scholar and writer Mohammad Hosseini (footballer, born 1979), Iranian footballer Mohammad Hosseini (protester) (1983–2023), Iranian protester who was executed by the government of Iran Mohammad Reza Hosseini (born 1989), Iranian footballer Mohamed Hussein al-Husseini (active 1991–1994), member of Hezbollah Mohammad Hosseini (footballer, born 1995), Iranian footballer Mohammad Hosseini (footballer, born 2000), Iranian footballer Mohamad Baker El Housseini (born 2002), Lebanese footballer Mohammad Ali Hosseini (active 2006–2023), Iranian politician Mohamed Husseini, Tazanian footballer