Van Dien is a surname of Dutch origin. Notable people with the surname include:

Casper Van Dien (born 1968), American actor Elsa van Dien (1914–2007), American astronomer Grace Van Dien (born 1996), American actress

See also Văn Điển Railway Station, railway station in Vietnam Van Dien House, historic house in Ridgewood, New Jersey Harmon Van Dien House, historic house in Paramus, New Jersey