Manso is a surname. Notable people with the surname include:
Alonso Manso (1460–1539), Spanish bishop Damián Manso (born 1979), Argentine footballer Frimpong Manso (born 1959), Ghanaian footballer and manager Giovanni Battista Manso (17th century), Italian (Naples) patron of the arts, Marchese of Villa Johann Kaspar Friedrich Manso (1760–1826), German historian and philologist José Manso de Velasco, 1st Count of Superunda (1688–1767), Spanish soldier and politician Juan Manso de Contreras, Spanish governor of New Mexico, 1656-1659 Shirley Frimpong-Manso (born 1977), Ghanaian film director, writer and producer Tomás Manso (1604-1659), Franciscan priest in New Mexico Will Manso (born 1975), American television journalist and host