Shope may refer to:
People Gertrude Shope (1925–2025), a South African trade unionist and politician Richard Shope (1901–66), an American virologist Robert Shope (1929–2004), an American virologist Simeon P. Shope (1837–1920), an American politician T. J. Shope (born 1985), an American politician
Other uses Shope papilloma virus, a virus that causes cancer in rabbits Shopi, a group of people in the Balkans USS Samaritan (AH-10), a ship also known as SS Shope Jennifer Shope, a character in the Canadian animated TV series Supernoobs