Mezen () is the name of several inhabited localities in Russia.
Urban localities Mezen, Mezensky District, Arkhangelsk Oblast, a town in Mezensky District of Arkhangelsk Oblast; administratively incorporated as a town of district significance
Rural localities Mezen, Plesetsky District, Arkhangelsk Oblast, a village in Undozersky Selsoviet of Plesetsky District of Arkhangelsk Oblast Mezen, Belokholunitsky District, Kirov Oblast, a village in Polomsky Rural Okrug of Belokholunitsky District of Kirov Oblast Mezen, Nolinsky District, Kirov Oblast, a village in Ludyansky Rural Okrug of Nolinsky District of Kirov Oblast