Van den Spiegel, Van de Spiegel or Van der Spiegel is a surname. Literally meaning "from the mirror", it is thought to usually refer to the home of a mirror maker.Spiegel, van der at the Database of Surnames in The Netherlands. Notable people with the surname include:

Adriaan van den Spiegel (1578–1625), Flemish physician active in Italy Bella van der Spiegel-Hage (born 1948), Dutch racing cyclist Laurens Pieter van de Spiegel (1736–1800), Dutch Grand Pensionary of Zeeland and Holland Tomas Van Den Spiegel (born 1978), Belgian basketball player Harry Vanderspeigle, a fictional alien and protagonist of Resident Alien (comics) (2012–2025) and Resident Alien (TV series) (2021–2025)

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