Asiedu is both a surname and a given name. Notable people with the name include:

Surname Elizabeth Asiedu, Ghanaian-born American economist John Alphonse Asiedu (born 1962), Ghanaian Roman Catholic bishop Joseph Richard Asiedu, Ghanaian judge and politician

Middle name

Johnson Asiedu Nkatie, Ghanaian politician

Given name Asiedu Attobrah (born 1995), Ghanaian professional footballer Asiedu Yirenkyi (1942–2018), Ghanaian playwright