Ampomah is a surname. Notable people with the surname include:
Alberta Ampomah (born 1994), Ghanaian weightlifter John Ampomah (born 1990), Ghanaian javelin thrower Joseph Ampomah Bosompem (born 1957), Ghanaian politician Kofi Martin Ampomah (1933–2011), Ghanaian aviator Opoku Ampomah (born 1996), Ghanaian footballer Owusu Ampomah (born 1985), Ghanaian footballer