Kyei is a surname. It may refer to:
Surname Afua Kyei (born 1982), British financial executive, CFO of the Bank of England F. P. Kyei, Ghanaian police officer, Inspector General of Police Grejohn Kyei (born 1995), French footballer Jeffrey Kyei (born 1989), German footballer Nana Kyei (born 1998), English footballer Obi Kyei (born 1994), Australian-British basketball player
Middle name Eyiah Kyei Baffour (born 1968), Ghanaian politician and member of the Ghanaian Parliament Osei Kyei Mensah Bonsu (born 1957), Ghanaian urban planner and politician. Kwadwo Kyei Frimpong (born 1946), Ghanaian politician and member of Parliament Jaren Kyei Merrell (born 1989), American drag queen known as Shea Couleé