Bolshoye Murashkino () is the name of several inhabited localities in Russia.
Urban localities Bolshoye Murashkino, Nizhny Novgorod Oblast, a work settlement in Bolshemurashkinsky District of Nizhny Novgorod Oblast
Rural localities Bolshoye Murashkino, Arkhangelsk Oblast, a village in Cherevkovsky Selsoviet of Krasnoborsky District of Arkhangelsk Oblast