Mamikonian () is a noble family which dominated Armenian politics between the 4th and 8th century.
Mamikonian or Mamikonyan or Mamigonian may also refer to:
Mamikonian dynasty John Mamikonean (Hovhannes Mamikonian), 7th-century author and historian Manuel Mamikonian, 4th-century Armenian ruler, military leader, and sparapet Mushegh I Mamikonian, 4th-century Armenian military leader and sparapet Vardan Mamikonian (also known as Saint Vardan; 393–451), Armenian military leader, martyr and saint of the Armenian Church Vassak Mamikonian, 4th-century Armenian military leader, sparapet for King Arsaces II (Arshak II)
Other people Saint Shushanik (born Vardeni Mamikonian c. 440–475), early medieval Christian martyr of Armenian origin Sophie Audouin-Mamikonian (born 1961), French-Armenian writer and author Vardan Mamikonian (musician), French-Armenian pianist