William Wightman may refer to:
William Wightman (English MP 1361-1391), MP for Huntingdon William Wightman (died 1580), MP William Wightman (judge) (1784–1863), British judge William Wightman (Canadian politician) (1929–2017) William May Wightman (1808–1882), American educator and clergyman
See also William Wightman Wood William Weightman William Weightman III