Four submarines of the Spanish Navy have borne the name Isaac Peral, after the Spanish naval officer and submarine pioneer Isaac Peral (1851–1895).

, an American-made submarine in commission from 1917 to 1932 , a in commission from 1928 to 1948 Isaac Peral (S-32), formerly , a updated to Guppy IIA configuration in commission from 1971 to 1987 , an commissioned in 2023

See also , an experimental submarine in commission from 1888 to 1890