Wiltse is a surname. Notable people with the surname include: Cadwallader Jackson Wiltse (1823–1900), American politician from Wisconsin David Wiltse (b. ?), American playwright Dottie Wiltse Collins (Dorothy Wiltse Collins, 1923–2008), American baseball player Gilbert C. Wiltse (1838–1893), American naval officer Hal Wiltse (1903–1983), American baseball player Hooks Wiltse (George Leroy Wiltse, 1879–1959), American baseball player Irving Wiltse (1900–1997), American politician from Nebraska Mark Wiltse (born 1988), American soccer player Snake Wiltse (Lewis DeWitt Wiltse, 1871–1928), American baseball player