Palatino is a family of typefaces.

Palatino may also refer to:

Palatino Express, a passenger train, formerly called the Rome Express, operating from 1890 Palatine Hill, also called Palatino, the centermost of the Seven Hills of Rome

People with the surname Giovanni Battista Palatino (c. 1515 – c. 1575), Italian calligrapher Raymond Palatino (born 1979), Filipino activist

See also Palatine (disambiguation)