Pamplemousse can refer to:

The Pamplemousse, a racehorse Pamplemousses District, a location on Mauritius Pomelo, a large citrus fruit known as 'pamplemousse' in French as spoken in France Grapefruit, a pomelo hybrid known by the name 'pamplemousse' in French as spoken in Quebec, Switzerland, and Belgium Frankie Pamplemousse, a cartoon character on The ZhuZhus "Pamplemousse", song by FKA Twigs on the mixtape Caprisongs (2022)

See also Pomplamoose, a musical duo Pomplamoose (album)