Oikonomou (), also transliterated as Ikonomou and Economou, is a Greek surname, deriving from the word oikonomos, "housekeeper, steward". It can refer to:
Aikaterini Oikonomou, birth name of Ketty Diridaoua, Greek actress Antonis Oikonomou (1785–1821), naval captain in the Greek War of Independence Constantin von Economo (1876–1931), Austrian neurologist Demetris Economou (born 1992), Cypriot association football player Dimitrios Oikonomou (1883–1957), Greek admiral Eleftherios N. Economou (born 1940), Greek Professor of Physics, father of Sophia Eleftherios Oikonomou (born 1956), Greek Chief of Police Evangelos Ikonomou (born 1987), Greek association football player George Economou (poet) (1934–2019), American poet George Economou (Shipbuilder) (born 1953), Greek billionaire shipowner George A. Economou, Sr. (1923–2003), optical systems expert Ioannis Ikonomou. (born 1964) Greek Translator, knows 43 living languages, 47 including dead languages James S. Economou (born 1951), surgical oncologist, tumor immunologist, and Vice Chancellor for Research at UCLA Manthos Oikonomou (1754–1820), Greek scholar and Ali Pasha's advisor Marios Oikonomou (1992–2026), Greek footballer Michalis Oikonomou (1888–1933), Greek impressionist painter Nicolas Economou (1953–1993), Cypriot composer Nick Economou, Australian political scientist Nikos Ekonomou (born 1973), Greek basketball player Panajotis Iconomou (born 1971), Greek-German baritone Pavlos Oikonomou-Gouras (1897–1991), Greek diplomat Sophia Economou, American physicist, daughter of Eleftherios Thanasis Oikonomou (born 1978), Greek swimmer Thomas Oikonomou (1864–1927), Greek actor