Jaenicke is a surname. Notable people with the surname include:
Anja Jaenicke (born 1963), German actress Frank Jaenicke (1892–1951), Co-operative Commonwealth Federation member of the Canadian House of Commons Hannes Jaenicke (born 1960), German actor Käte Jaenicke (1923-2002), German actress
See also Jänicke (disambiguation)