McFadyean is a surname. Notable people with the surname include:

Andrew McFadyean (18871974), British diplomat and economist Colin McFadyean (born 1943), England International rugby union player and Captain John McFadyean (18531941), British veterinary surgeon Melanie McFadyean (1950–2023), British journalist and lecturer Ben McFadyean (born 1969), British sports journalist and academic