McCallion is a surname. Notable people with the surname include:
Eddie McCallion (born 1979), Northern Irish footballer Elisha McCallion (born 1982), Northern Irish politician Enda McCallion (born 1967), Irish film director Hazel McCallion (1921–2023), Canadian mayor Mac McCallion (1950–2018), New Zealand rugby union coach Marcus McCallion (born 1971), English graphic designer and typographer Seamus McCallion, (born 1964), Irish rugby league player