Mauricie–Bois-Francs () was a former administrative region of Quebec. It was created in 1966 along with the other nine original administrative regions of Quebec. It ceased to exist on July 30, 1997 (or August 20, 1997, upon publication in the Gazette officielle du Québec) when it was split into the modern-day administrative regions of Mauricie and Centre-du-Québec.
It consisted of the following regional county municipalities: Francheville Le Centre-de-la-Mauricie Le Haut-Saint-Maurice Maskinongé Mékinac
which became part of Mauricie, and:
Arthabaska Bécancour Drummond L'Érable Nicolet-Yamaska
which became part of Centre-du-Québec.
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