Epes may refer to:
People Given name Epes Randolph (1856–1921), American civil engineer Epes Sargent (poet) (1813–1880), American writer and editor Epes Sargent (soldier) (1690–1762), American soldier and landowner Epes W. Sargent (1872–1938), American vaudeville critic
Surname James F. Epes (1842–1910), American politician Louis S. Epes (1882–1935), American lawyer, judge and politician Maria Epes (born 1950), American artist Sidney Parham Epes (1865–1900), American politician Places Epes, Alabama, United States
See also EPE (disambiguation)