Caston is a surname. Notable people with the surname include:

Douglas Caston (1917–1996), Canadian newspaper publisher and politician Geoffrey Caston (born 1926), Registrar of the University of Oxford Leonard Caston (1917–1987), American blues musician Leonard Caston Jr., rhythm and blues musician Rodney Caston (born 1977), American systems engineer and writer Toby Caston (1965–1994), American footballer