Guégan is a Breton surname. Notable people with the surname include:
Élodie Guégan (born 1985), French middle-distance runner Hervé Guégan (born 1963), French footballer Jean-Baptiste Guégan (born 1983), French singer Marc-Adolphe Guégan (1891–1959), French journalist and poet Olivier Guégan (born 1972), French footballer Raymond Guégan (1921–2007), French cyclist