Crépin is a French surname. Notable people with the surname include:
Alain Crépin (born 1954), Belgian saxophonist and composer François Crépin (1830–1903), Belgian botanist Jean Crépin (1908–1996), French Army general Louis-Philippe Crépin (1772–1851), French painter Malin Crépin (born 1978), Swedish actress Margit Otto-Crépin (1945–2020), French equestrian
See also Saint-Crépin (disambiguation), various communes in France Crépin Point, headland in the South Shetland Islands